No single package is best for everyone. Below, per system: where it excels, where it thins out, and who it is the right choice for.
Odoo
Odoo is an open-source business platform running CRM, sales, inventory, purchasing, manufacturing, projects, HR, accounting and a webshop on one database. Its strength is breadth and flexibility: start with the modules you need and extend without a second system. Since version 16 (late 2022) its Dutch accounting is mature - bank feeds, VAT and ICP filings. The open-source foundation means you own your customizations, with no vendor lock-in. Less suited if you need a deep, industry-specific niche system, or expect it to work perfectly without configuration. Entry around €25 per user per month.
In shortStrongest if you want one platform for the whole business - webshop, inventory, finance and CRM on one model - with customizations you own and no vendor lock-in.
AFAS
AFAS is a Dutch all-in-one package that excels at HR, payroll and administration - a closed, highly standardized platform popular in professional services, healthcare, construction and education. Its strength is the integrated Dutch payroll run and tight processes. The flip side: beyond finance and HR it thins out, customization is limited by the closed model, and the all-in price per employee rises as you grow - including for people who barely use the system. Strong if HR and payroll are your core; narrower for manufacturing, webshop or international roll-out.
In shortBest when HR and Dutch payroll are your core; narrower and less flexible once you move beyond finance/HR (manufacturing, webshop, projects).
Exact
Exact started as accounting software and grew into an ERP for the Dutch SMB, strong in trade and logistics. Dutch accounting is the core and is proven mature - VAT, RGS, SBR. For administration and finance it is a trusted choice. It narrows as a broad business platform: trade, manufacturing, projects and e-commerce lean on connectors or a second package sooner. Exact Online (cloud) and Globe+ (on-premise) serve different segments; note that Globe is on an end-of-life path. Best choice when your need sits mainly in accounting and invoicing.
In shortTrusted Dutch accounting; narrower as a broad business platform - trade, manufacturing and projects lean on connectors sooner.
Microsoft Dynamics 365 BC
Microsoft Dynamics 365 Business Central is Microsoft's cloud ERP for the mid-market. Its biggest asset is integration: if your organisation already lives deep in the Microsoft stack - Teams, Outlook, Power BI, Azure AD - Business Central feels like a natural extension. Customization runs broad via the AL language and a large partner network; Dutch accounting comes through a partner localization. The flip side: implementation is heavier and the licence starts around €65 per user per month, higher than Odoo at comparable scope. Logical when Microsoft is your standard; less obvious when it is not.
In shortLogical if your organisation already lives in Microsoft (Teams, Power BI, Azure AD); heavier to implement and pricier at comparable scope.
SAP Business One
SAP Business One is the SAP variant for the larger SMB - typically companies of 50 to 250 employees, often with international sites. You get the SAP name, a solid core for finance and inventory, and localization for the Netherlands. Customization runs via partners and the SDK, which is powerful but specialist. The price sits higher - around €90 per user per month - and implementation is heavier than the Dutch packages or Odoo. The right choice if you scale internationally and deliberately pick the SAP ecosystem; for the average Dutch SMB often heavier and pricier than needed.
In shortFor growing SMBs with international ambition and a preference for SAP; expect higher cost and a heavier implementation.
Oracle NetSuite
Oracle NetSuite is a cloud ERP (SaaS) built for fast-growing, international companies. Its strength is multi-entity: consolidating across countries, currencies and subsidiaries in one system, with a native webshop (SuiteCommerce) and broad extensibility via SuiteScript. Dutch accounting runs through a partner. Against that sits a price that starts high - around €110 per user per month - plus a substantial implementation. For an internationally operating scale-up that must consolidate across entities, that is defensible. For the average Dutch SMB, NetSuite is usually too heavy and too pricey for what you get back.
In shortStrong for international, fast-scaling companies that consolidate across entities; often too heavy and too pricey for the Dutch SMB.